| 2022-04-02 08:30:14April 2, 2022 | Grace Baptist vs Diocese of Greensburg | 08:30:148:30 am | 74 - 97 | N/A |
| 2022-04-02 10:00:15April 2, 2022 | Friendship vs St. Elizabeth | 10:00:1510:00 am | 94 - 88 | N/A |
| 2022-04-07 19:00:55April 7, 2022 | Diocese of Greensburg vs ACAC | 19:00:557:00 pm | 129 - 99 | N/A |
| 2022-04-07 20:30:32April 7, 2022 | Friendship vs Crossroads | 20:30:328:30 pm | 63 - 75 | N/A |
| 2022-04-09 10:00:32April 9, 2022 | St. Elizabeth vs Grace Baptist | 10:00:3210:00 am | 91 - 65 | N/A |
| 2022-04-09 11:30:33April 9, 2022 | Friendship vs ACAC | 11:30:3311:30 am | 101 - 98 | N/A |
| 2022-04-16 08:30:39April 16, 2022 | ACAC vs Crossroads | 08:30:398:30 am | 80 - 105 | N/A |
| 2022-04-16 10:00:59April 16, 2022 | St. Elizabeth vs Diocese of Greensburg | 10:00:5910:00 am | 106 - 119 | N/A |
| 2022-04-16 11:30:11April 16, 2022 | Grace Baptist vs Beulah Presbyterian | 11:30:1111:30 am | 119 - 57 | N/A |
| 2022-04-21 19:00:35April 21, 2022 | Crossroads vs Beulah Presbyterian | 19:00:357:00 pm | 105 - 61 | N/A |
| 2022-04-21 20:30:12April 21, 2022 | Grace Baptist vs Friendship | 20:30:128:30 pm | 96 - 117 | N/A |
| 2022-04-23 08:30:40April 23, 2022 | Crossroads vs Grace Baptist | 08:30:408:30 am | 72 - 76 | N/A |
| 2022-04-23 10:00:06April 23, 2022 | ACAC vs St. Elizabeth | 10:00:0610:00 am | 0 - 2 | N/A |
| 2022-04-23 11:30:30April 23, 2022 | Diocese of Greensburg vs Beulah Presbyterian | 11:30:3011:30 am | 134 - 81 | N/A |
| 2022-04-23 13:00:52April 23, 2022 | Diocese of Greensburg vs Friendship | 13:00:521:00 pm | 102 - 101 | N/A |
| 2022-04-28 19:00:43April 28, 2022 | Beulah Presbyterian vs St. Elizabeth | 19:00:437:00 pm | 67 - 138 | N/A |
| 2022-04-28 20:30:15April 28, 2022 | Crossroads vs Diocese of Greensburg | 20:30:158:30 pm | 109 - 117 | N/A |
| 2022-04-30 08:30:37April 30, 2022 | St. Elizabeth vs Crossroads | 08:30:378:30 am | 108 - 112 | N/A |
| 2022-04-30 10:00:58April 30, 2022 | ACAC vs Grace Baptist | 10:00:5810:00 am | 103 - 94 | N/A |
| 2022-04-30 11:30:21April 30, 2022 | Beulah Presbyterian vs Friendship | 11:30:2111:30 am | 0 - 2 | N/A |
| 2022-05-07 08:30:34May 7, 2022 | #2 Crossroads vs #7 Beulah Presbyterian | 08:30:348:30 am | 86 - 76 | N/A |
| 2022-05-07 10:00:12May 7, 2022 | #3 Friendship vs #6 ACAC | 10:00:1210:00 am | 106 - 91 | N/A |
| 2022-05-07 11:30:51May 7, 2022 | #4 St. Elizabeth vs #5 Grace Baptist | 11:30:5111:30 am | 79 - 61 | N/A |
| 2022-05-12 19:00:23May 12, 2022 | #1 Diocese of Greensburg vs #4 St Elizabeth (Semifinal #1) | 19:00:237:00 pm | 95 - 109 | N/A |
| 2022-05-12 20:30:16May 12, 2022 | #2 Crossroads vs #3 Friendship (Semifinal #2) | 20:30:168:30 pm | 89 - 64 | N/A |
| 2022-05-19 20:00:34May 19, 2022 | #2 Crossroads vs #4 St. Elizabeth (Championship) | 20:00:348:00 pm | 97 - 122 | N/A |